Stem Cells from Fat Used to Grow Teen's Missing Facial Bones

Surgeons report success in first human bone growth procedure using fat stem cells--with no culturing necessary
By Katherine Harmon
October 15, 2009

Stem cells so far have been used to mend tissues ranging from damaged hearts to collapsed tracheas. Now the multifaceted cells have proved successful at regrowing bone in humans. In the first procedure of its kind, doctors at Cincinnati Children's Hospital Medical Center replaced a 14-year-old boy's missing cheekbones—in part by repurposing stem cells from his own body.

The technique, should it be approved for widespread use, could benefit some seven million people in the U.S. who need more bone—everyone from cancer patients to injured war veterans.

"This is sort of the holy grail for a number of different surgeons," says Jesse Taylor, a surgeon and researcher in the hospital's Division of Plastic Surgery and one of the procedure's lead physicians. The procedure could be used in plastic, orthopedic and neural surgeries, he notes. Some bone tissue had previously been generated from stem cells in the lab, but this marks hope for a surgical solution for those who need additional bone. the rest