Man’s Life Saved With Artificial Trachea Using Stem Cells

by David Prentice, Ph.D.
1/16/12

A 30-year-old Baltimore man is now back home recuperating from surgery in Sweden that implanted an artificial trachea made with his own adult stem cells.

Christopher Lyles was diagnosed with inoperable tracheal cancer. He found Italian Dr. Paolo Macchiarini, who is a Visiting Professor at the Karolinska Institute in Stockholm, Sweden, who has constructed and transplanted replacement tracheas, using the patient’s own bone marrow adult stem cells to build the new tissue. Lyles traveled to Sweden in November to have the surgery; he returned home this week with his new implanted trachea.

In a telephone interview, Lyles said he was “feeling good”, and “just thankful for a second chance at life.” He was looking forward to watching his 4-year-old daughter grow up.

“He went home in very good shape,” said Dr. Macchiarini. Macchiarini said that Mr. Lyles adult stem cells were placed onto the synthetic windpipe scaffold and grown in a bioreactor for two days, then transplanted into his body after removal of his tumorous trachea.
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