Study Shows Adult Stem Cell Grafts Help Paralyzed

Sunday, 18 October 2009

Excerpt:
In the study, 20 patients with severe chronic spinal cord injuries received a treatment combination of partial scar removal, transplantation of nasal tissue containing stem cells to the site of the spinal cord injury and rehabilitation. All of the patients had total paralysis below the level of their spinal cord injury before the treatment.

“This may be the first clinical study of patients with severe, chronic spinal cord injury to report considerable functional improvement in some patients with a combination treatment,” Peduzzi-Nelson said. “Normally, in people with spinal cord injuries that happened more than 18 months ago, there is little improvement.”

The injuries in the study patients were 18 months to 15 years old. The patients, ages 19 to 37, had no use of their legs before the treatment. One paraplegic treated almost three years after the injury now ambulates with two crutches and knee braces. Ten other patients ambulate with physical assistance and walkers (with and without braces). One 31-year-old male tetriplegic patient uses a walker without the help of knee braces or physical assistance. When the stem cell transplant and scar removal process was combined with an advanced form of rehabilitative training that employs brain-initiated weight-bearing movement, 13 patients improved in the standard measures used to assess functional independence and walking capabilities. the rest